Russia on Saturday accused the West of seeking regime change in Moscow, raising tensions over the conflict in Ukraine in the worst crisis in relations since the end of the Cold War.
Foreign Minister Sergei Lavrov spoke out against Western sanctions on Russia after U.S. Vice President Joe Biden hinted Friday at possible further measures over its "unacceptable" role in the former Soviet state.
Kiev's defense minister charged Saturday that there were 7,500 Russian troops in eastern Ukraine, although Russia denies claims that it provides military support to pro-Moscow separatists locked in conflict with government forces.
"The West is showing unambiguously that they do not want to force (Russia) to change policy, they want to achieve a change of regime," Lavrov told a forum of political analysts in Moscow.
"Now public figures in Western countries are saying that it's necessary to introduce sanctions that would destroy the economy and rouse public protests," he added in comments cited by TASS news agency.
The United States and European Union have imposed several rounds of sanctions on Moscow over Ukraine targeting the key energy, defense and finance sectors. These have sent the ruble into freefall and inflation soaring.
On a visit to Kiev on Friday, Biden accused Russia of failing to honor a peace agreement signed in September, which includes a tattered ceasefire in eastern Ukraine.
"So long as that continues, Russia will face rising costs, greater isolation," Biden added.
Some 4,300 people have been killed in the conflict in seven months, according to the United Nations. Nearly 1,000 have died since the ceasefire came into effect.
Lavrov's comments came after Ukraine's Defense Minister Stepan Poltorak claimed Russia had thousands of troops in the east and vowed to boost Kiev's military capacity.
"Unfortunately, the stabilisation of the situation in the east of Ukraine does not depend only on us," Poltorak said. "The presence of 7,500 representatives of Russian armed forces in Ukraine destabilizes the situation and prevents us from stabilizing it."
Cash-strapped Ukraine also plans to "increase the strength of the armed forces" and boost levels of arms and equipment, he added, pledging that this would take place "in the nearest time" but not giving a specific timeframe.
The minister's comments came after Ukraine's new coalition declared that joining NATO was a priority, stipulating that a law be passed by the end of the year confirming the intention to push for membership.
The five-party coalition, agreed on Friday following October elections, features the groupings of President Petro Poroshenko, Prime Minister Arseniy Yatsenyuk and former premier Yulia Tymoshenko.
But experts play down Ukraine's chances of joining NATO anytime soon.
"The idea of the alliance accepting a country in armed conflict with Russia is science fiction," said Vasyl Filipchuk, a former senior Ukrainian official who is chairman of the International Center for Policy Studies in Kiev.
NATO, a military alliance of 28 nations including the United States, this week warned of a "very serious build-up" of Russian troops, artillery and air defense systems inside Ukraine and on the Russian side of the border.
In the latest batch of U.S. assistance to Ukraine, three radars designed to detect incoming mortar fire were delivered Friday following Biden's visit, with a total of 20 arriving in the next few weeks.
The United States has so far ruled out providing weapons and ammunition to Ukraine, approving only "non-lethal" assistance such as radars, night vision goggles and body armor.
Ukraine's head of security operations in the east said that 20 units of Russian "military hardware" had crossed the border Saturday.
In the past 24 hours, four Ukrainian soldiers were killed and one civilian have been killed in eastern Ukraine, officials said.
Ukraine's military on Friday accused Russia of shelling its territory for the first time since the ceasefire was signed.
Also on Friday, Kiev marked a year since the start of protests on the city's Independence Square which led to the ousting of the previous pro-Moscow regime, Russia's annexation of Crimea and the conflict in the east.
On Saturday, Ukraine marks the 10th anniversary of the Orange Revolution and holds a day of mourning for millions of victims of the Soviet-era famine in the 1930s.
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