A fresh round of explosions was heard in northwestern Iran on Friday, state television reported, after Israel carried out a wave of strikes on multiple cities.

Israel launched fresh attacks on a key underground uranium enrichment facility in central Iran on Friday, Iranian state media reported.

U.S. President Donald Trump urged Iran on Friday to "make a deal," warning that there will be more "death and destruction" after Israel launched deadly strikes targeting Iranian nuclear facilities.

His comments on his Truth Social platform came after Israel pounded Iran in a series of air raids on Friday, striking 100 targets.

Israel's defense ministry said Friday that Israeli air strikes across Iran had "neutralized" most of the senior leadership of the Iranian Revolutionary Guards' Air Force.

"The defense minister was informed that most of the Revolutionary Guard Air Force leadership was neutralized while convening at their underground headquarters," the ministry said in a statement.

Hezbollah warned Friday that Israel's strikes on its main foreign backer Iran "threaten to ignite the region".

The group, which fought a two-month war with Israel last year, condemned the "brutal Israeli aggression" against Iranian nuclear facilities and scientists and said Israel was "engaging in adventures that threaten to ignite the entire region".

U.S. President Donald Trump told Fox News he was aware Israel was going to conduct strikes on Iran before it happened, and stressed that Tehran "cannot have a nuclear bomb," according to the US broadcaster.

His comments to Fox came after Israel pounded Iran in a series of air raids on Friday, striking 100 targets including nuclear and military sites.

Iran's supreme leader Ayatollah Ali Khamenei swiftly appointed new Revolutionary Guards and armed forces chiefs to replace those killed in targeted Israeli strikes on Friday.

In separate decrees, Khamenei named Mohammad Pakpour to replace Hossein Salami as commander of the Islamic Revolutionary Guard Corps, and Abdolrahim Mousavi to replace Mohammad Bagheri as chief of the armed forces general staff.

The Israeli military said it hit the underground uranium enrichment centrifuges at Iran's vast Natanz facility as part of the wave of strikes it carried out on Friday.

"The underground area of the site was damaged. This area contains a multi-storey enrichment hall with centrifuges, electrical rooms and additional supporting infrastructure," the military said in a statement.

Iran sharply criticized the UN nuclear watchdog on Friday, accusing it of "silence" over Israel's strikes on its nuclear facilities and scientists.

In a statement, Iran's Atomic Energy Organization said it considers the "silence" from the International Atomic Energy Agency "as a form of cooperation with the Zionist regime," adding that the Israeli attack was a "defeat for the IAEA resulting from its unjustifiable shortcomings".

Defense Minister Israel Katz warned that Israel would "eliminate" its foes after it carried out air strikes on Iran targeting military and nuclear sites.

"The precise targeting of senior commanders of the Revolutionary Guards, the Iranian military, and nuclear scientists -- all of whom were involved in advancing the plan to destroy Israel -- sends a strong and clear message: those who work toward Israel's destruction will be eliminated," Katz said in a statement.

Jordan said it would not allow its airspace to be violated and vowed not to become a "battleground" in any regional conflict, after Israel conducted strikes on Iran on Friday.

Jordan intercepted multiple drones and missiles fired by Iran at Israel in October 2024.