Iran's ruling clerics on Sunday appointed the slain leader's son, Ayatollah Mojtaba Khamenei, as the country's new supreme leader, defying threats from the United States and Israel to oppose him.

Israel struck the Palestinian refugee camp of Ain al-Hilweh in southern Lebanon on Sunday, Lebanese state media reported, amid the new war between Israel and Iran-backed Hezbollah.

Israeli strikes on Lebanon have killed 394 people in the past week, including 83 children and 42 women, the country's health minister said Sunday.

Rakan Nassereddine also said at a press conference that nine rescue workers were among the dead, condemning attacks on medical teams and ambulances.

More than 100 Iranians, including some diplomats, were evacuated from Beirut overnight on a Russian plane, a Lebanese official told AFP on Sunday.

"A total of 117 Iranians, including diplomats and embassy staff, were evacuated on a Russian plane that left Beirut overnight from Saturday to Sunday," the official said on condition of anonymity.

Iran's Revolutionary Guards said on Sunday that they had launched missiles towards the Israeli cities of Tel Aviv and Bersheeva, as well as an airbase in Jordan.

"The 28th wave of the Operation Honest Promise 4 was launched by the next-generation missiles of the Guards aerospace force against the areas of Beersheva, Tel Aviv, and the Al-Azraq airbase," the Guards said in a statement, according to state TV.

Iran's Revolutionary Guards said Sunday that the country's forces could fight an intense war for six months against the United States and Israel, which said it struck Tehran's commanders at a seaside hotel in the heart of Beirut.

As the conflict spilled into its second week, the regional repercussions spiraled, with Saudi Arabia intercepting a wave of drones headed for targets including the diplomatic quarter in capital Riyadh and Kuwait saying an attack hit fuel tanks at its international airport.

The health ministry said Sunday that an Israeli strike on a hotel in central Beirut killed at least four people, with Israel saying it had targeted commanders from Iran's Revolutionary Guards.

Lebanon was drawn into the Middle East war on Monday, when Hezbollah attacked Israel in response to the killing of Iranian supreme leader Ayatollah Ali Khamenei during U.S.-Israeli strikes.

The Israeli military on Saturday warned the remaining residents of Beirut's southern suburbs, where Hezbollah holds sway, to evacuate immediately.

Lebanese Army chief Rodolphe Haykal said Saturday that the Israeli soldiers who made helicopter landings in east Lebanon wore military uniforms similar to those of the Lebanese Army and used military vehicles and ambulances similar to those of the Hezbollah-linked Islamic Health Authority.

Haykal added that Israeli attacks targeting Lebanon were hindering the implementation of the army's plan to disarm Hezbollah.

Israel's military on Saturday warned residents in a district of Lebanon's Tyre to evacuate ahead of strikes, and reiterated a demand for people to leave the area south of the Litani River.