Pfizer has begun a study comparing its original COVID-19 vaccine with doses specially tweaked to match the hugely contagious omicron variant.

Pfizer and its partner BioNTech announced the study on Tuesday.

Thailand on Tuesday became the first country in Asia to approve the de facto decriminalization of marijuana, though authorities have left a grey area around its recreational use.

Health Minister Anutin Charnvirakul announced that the Narcotics Control Board had approved the dropping cannabis from the ministry's list of controlled drugs.

Japan's government plans to put the majority of the country under pre-emergency status and extend COVID-19 restrictions as omicron cases have surged and threatened to disrupt basic services like hospitals and schools.

Prime Minister Fumio Kishida said Monday that he will tighten anti-virus measures in 18 more prefectures, including Hokkaido in the north to Osaka and Kyoto in western Japan, until Feb. 20. This will be in addition to areas where similar restrictions are already in place or to be further extended — including Tokyo, Okinawa, Yamaguchi and Hiroshima.

People who aren't vaccinated against COVID-19 are no longer allowed in France's restaurants, bars, tourist sites and sports venues unless they recently recovered from the virus.

The new law came into effect Monday requiring a "vaccine pass" that is central to the government's anti-virus strategy.

A cluster of COVID-19 cases in Beijing has prompted authorities to test millions and impose new measures two weeks ahead of the opening of the Winter Olympics, even as the city of Xi'an in north-central China lifted on Monday a monthlong lockdown that had isolated its 13 million residents.

Officials in Beijing said they would conduct a second round of mass testing of the Fengtai district's 2 million residents, where the majority of the capital's 40 coronavirus cases since Jan. 15 have been found. That came a day after authorities announced that anyone who buys or who has bought fever, cough or certain other medicines in the past two weeks would be required to take a COVID-19 test within 72 hours.

Thousands of people have gathered in European capitals to protest vaccine passports and other requirements governments have imposed in hopes of ending the coronavirus pandemic.

Demonstrations took place in Athens, Helsinki, London, Paris and Stockholm.

Adele has postponed a 24-date Las Vegas residency hours before it was to start, citing delivery delays and coronavirus illness in her crew.

The chart-topping British singer said she was "gutted" and promised to reschedule the shows.

Australia on Friday reported its deadliest day of the pandemic with 80 coronavirus fatalities, as an outbreak of the omicron variant continued to take a toll.

But Dominic Perrottet, premier of the most populous state, New South Wales, said a slight decrease in hospitalizations gave him some hope about the strain the outbreak is putting on the health system.

Restaurants and bars will close early in Tokyo and a dozen other areas across Japan beginning Friday as the country widens COVID-19 restrictions due to the omicron variant, which has caused cases to surge to new highs in metropolitan areas.

The restraint, which is something of a pre-state of emergency, is the first since September and is scheduled to last through Feb. 13. With three other prefectures — Okinawa, Hiroshima and Yamaguchi — under similar measures since early January, the state of restraint now covers 16 areas, or one-third of the country.

As he starts his second term as U.N. secretary-general, Antonio Guterres said Thursday the world is worse in many ways than it was five years ago because of the COVID-19 pandemic, the climate crisis and geopolitical tensions that have sparked conflicts everywhere — but unlike U.S. President Joe Biden he thinks Russia will not invade Ukraine.

Guterres said in an interview with The Associated Press that the appeal for peace he issued on his first day in the U.N.'s top job on Jan. 1, 2017 and his priorities in his first term of trying to prevent conflicts and tackle global inequalities, the COVID-19 crisis and a warming planet haven't changed.