The U.S. Navy has deployed a guided-missile submarine capable of carrying up to 154 Tomahawk missiles to the Middle East, a spokesman said Saturday, in what appeared to be a show of force toward Iran following recent tensions.

The Navy rarely acknowledges the location or deployment of submarines. Cmdr. Timothy Hawkins, a spokesman for the 5th Fleet based in the Gulf nation of Bahrain, declined to comment on the submarine's mission or what had prompted the deployment.

The European Union on Saturday condemned deadly attacks in Israel and a barrage of rockets fired from Lebanon that triggered Israeli strikes and called for "restraint."

"The EU expresses its total condemnation of these acts of violence. This must cease," the bloc's foreign policy chief Josep Borrell said in a statement after Friday's attacks in Israel.

The United States has said it supports ally Israel's "right to self-defense" after deadly attacks as well as rocket fire from Lebanon that triggered Israeli strikes.

"The targeting of innocent civilians of any nationality is unconscionable. The United States stands with the government and people of Israel," State Department spokesman Vedant Patel said in a statement.

Israeli Prime Minister Benjamin Netanyahu mobilized police and army reserves after separate attacks killed three people, including an Italian tourist, in the West Bank and Tel Aviv, in the latest escalation of deadly violence.

Despite appeals for restraint, violence has surged since Israeli police clashed with Palestinians Wednesday inside Jerusalem's al-Aqsa mosque, with Israel bombarding both Gaza and Lebanon following rocket fire by Palestinian militants.

Russia has called on Israel, the Palestinians and Lebanon to end the "escalation" of violence, saying it was "deeply" concerned.

"We call on the parties involved in the conflict to refrain from confrontational steps, to act in the interests of preventing further escalation, ending violence and restoring a sustainable ceasefire," the foreign ministry said.

British Foreign Secretary James Cleverly on Friday appealed on "all parties" to de-escalate after Israel bombarded the Gaza Strip and Lebanon in retaliation for several dozen rockets fired from both territories.

"Now is the time for all parties across the region to de-escalate tensions," he said, condemning rocket attacks on Israel from Gaza and southern Lebanon, and noting London recognizes "Israel's right to self-defense."

An alleged Palestinian shooting attack in the northern occupied West Bank killed two Israeli women and seriously wounded another, Israeli medics said, the latest violence after Israeli warplanes struck southern Lebanon in a significant escalation.

Israel's Magen David Adom rescue service said that two women in their 20s were killed and another woman in her 40s was seriously wounded near the settlement of Hamra in the Jordan Valley. The medics said they pulled the three unconscious women out of their car, which had apparently crashed after a Palestinian allegedly opened fire at it from a nearby vehicle. The Israeli military said security forces were searching for the attacker.

Israel bombarded the Gaza Strip and Lebanon before dawn on Friday, saying it was targeting Palestinian militant group Hamas in retaliation for several dozen rockets fired at Israel from both territories.

It was the biggest salvo fired from Lebanon since Israel fought a devastating 34-day war with Hezbollah in 2006 and the first time Israel has confirmed an attack on Lebanese territory since April 2022.

The Israeli military struck targets in the Gaza Strip early Friday, pushing the region toward a wider conflagration after a day of rocket fire along Israel's northern and southern borders following two days of unrest at Jerusalem's most sensitive holy site. Gaza militants quickly fired off a new barrage of rockets, setting off air raid sirens across southern Israel.

The Israeli airstrikes set off at least four loud explosions in Gaza. The Israeli military said it struck a pair of tunnels and two weapons-manufacturing sites.

Hamas chief Ismail Haniyeh said Thursday Palestinians "will not sit with their arms crossed" in the face of Israeli "aggression" against the al-Aqsa mosque in Jerusalem.

He was speaking in Beirut after Israel blamed Palestinian militants for firing a barrage of rockets from Lebanon at northern Israel.