Hamas political leader Ismail Haniyeh was killed on Wednesday in an Israeli strike in Iran, the group said, in an act that has stunned the international community.

Israel has not commented on the death but many countries have warned that it will have a major impact on efforts to bring a ceasefire in the Gaza war. Here are the key reactions:

Hezbollah condemned Israel's killing of Hamas leader Ismail Haniyeh on Wednesday, warning his death will only increase the resolve of Iran-backed "resistance" groups.

Hamas said Haniyeh was killed in an Israeli strike in the Iranian capital, where he was attending the swearing-in of the country's new president, and vowed the act "will not go unanswered".

Ismail Haniyeh, Hamas' supreme leader in exile who landed on Israel's hit list after the militant group staged its surprise Oct. 7 attacks, was killed in an airstrike in the Iranian capital early Wednesday. He was 61.

Hamas said Haniyeh was killed at his residence in Tehran in an Israeli airstrike after he attended the swearing-in ceremony of Iran's new president. Israel has not commented on the accusation.

Iran’s President Masoud Pezeshkian condemned the killing of Hamas leader Ismail Haniyeh in Tehran on Wednesday.

He said in a post on the X platform that his country will defend its territorial integrity and make those responsible regret their actions.

The United Nations human rights office issued a report Wednesday saying Palestinian detainees taken by Israeli authorities since the Oct. 7 attacks have faced waterboarding, sleep deprivation, electric shocks and other torture and mistreatment.

The report on detention says Israel’s prison service held more than 9,400 “security detainees” as of the end of June, and some have been held in secret without access to lawyers or respect for their legal rights.

Hamas leader Ismail Haniyeh was killed by an airstrike in the Iranian capital, Iran and the militant group said early Wednesday, blaming Israel for a shock assassination that risks escalating the regional conflict on multiple fronts.

There was no immediate comment from Israel, which has vowed to kill Haniyeh and other Hamas leaders over the group's Oct. 7 attack on southern Israel. The strike came just after Haniyeh had attended the inauguration of Iran's new president in Tehran, Iran said.

Gaza's civil defense agency said Tuesday that an Israeli operation in and around the territory's second city of Khan Younis has killed about 300 people since it began on July 22.

"Since the beginning of the Israeli ground invasion of the eastern part of Khan Yunis province, the civil defense and medical teams have recovered approximately 300 bodies of martyrs, many of them decomposed," agency spokesman Mahmoud Bassal told AFP.

A steady stream of miserable children and worried parents flowed into the dermatology office at Nasser Hospital in central Gaza.

A toddler with a blue hair bow sobbed as her mother showed how the red and white spots covering her face have spread to her neck and chest. Another woman lifted her little boy's clothes to reveal the rashes on his back, butt, thighs and stomach. On his wrists, he had open sores from scratching. A father stood his daughter on the desk so the doctor could examine the lesions on her calves.

Nine Israeli soldiers were due to appear before a military court for an initial hearing Tuesday over what a defense lawyer said were allegations of sexual abuse of a Palestinian at a shadowy facility where Israel has held prisoners from Gaza during the war.

The investigation has stoked tensions between the military command and hard-line nationalists in Prime Minister Benjamin Netanyahu's government who advocate an even harsher hand in Israel's conduct of the 10-month-old war in Gaza.

Two days after a rocket slammed into a soccer pitch in the Israel-controlled Golan Heights, killing 12 children, many questions remain about the attack on the Druze town of Majdal Shams.

Israel accused Hezbollah in Lebanon of deliberately targeting civilians, while Hezbollah quickly issued a rare denial of any responsibility for the attack.