Iran's ruling clerics on Sunday appointed the slain leader's son, Ayatollah Mojtaba Khamenei, as the country's new supreme leader, defying threats from the United States and Israel to oppose him.

Iran's Revolutionary Guards said on Sunday that they had launched missiles towards the Israeli cities of Tel Aviv and Bersheeva, as well as an airbase in Jordan.

"The 28th wave of the Operation Honest Promise 4 was launched by the next-generation missiles of the Guards aerospace force against the areas of Beersheva, Tel Aviv, and the Al-Azraq airbase," the Guards said in a statement, according to state TV.

Iran's Revolutionary Guards said Sunday that the country's forces could fight an intense war for six months against the United States and Israel, which said it struck Tehran's commanders at a seaside hotel in the heart of Beirut.

As the conflict spilled into its second week, the regional repercussions spiraled, with Saudi Arabia intercepting a wave of drones headed for targets including the diplomatic quarter in capital Riyadh and Kuwait saying an attack hit fuel tanks at its international airport.

U.S. President Donald Trump threatened to escalate the bombing of Iran on Saturday as Iranian President Masoud Pezeshkian vowed that he would never surrender, despite a fresh blitz of U.S. and Israeli air strikes that set a Tehran airport ablaze.

Israel confirmed some of the biggest raids since the aerial bombardment of Iran began last Saturday, with a military academy, an underground command center and a missile storage facility named as targets.

Here are the latest events in the Middle East war on Saturday:

President Donald Trump said Friday that only Iran's "unconditional surrender" would bring an end to the Middle East war, as Tehran was rocked by some of the heaviest U.S.-Israeli strikes of the spiralling, week-long conflict.

Israel's military said Friday it had identified "simultaneous and coordinated" missile launches by Iran and Hezbollah aimed at overwhelming Israeli air defenses.

"We... identified yesterday simultaneous and coordinated attacks between Iran and Hezbollah, simultaneous missile launching from both Iran and Lebanon in an attempt to overwhelm our aerial defense systems," military spokesman Lieutenant Colonel Nadav Shoshani told journalists.

Fresh strikes rocked Iran and Lebanon Friday as Israel and the United States stepped up their attacks in the sprawling Middle East war, with powerful explosions shattering the skies of Tehran.

U.S. President Donald Trump on Thursday insisted he should have a role in picking Iran’s next supreme leader after the killing of Ayatollah Ali Khamenei, whose son he said he found unacceptable.

Iran's military said on Thursday that it had launched a drone attack against a U.S. military site in Kuwait.

"Drone units of the armed force's navy targeted a site of the U.S. forces Camp Udairi in Kuwait using combat drones," the army said in a statement broadcast by state TV.