A fresh round of explosions was heard in northwestern Iran on Friday, state television reported, after Israel carried out a wave of strikes on multiple cities.

Israel launched fresh attacks on a key underground uranium enrichment facility in central Iran on Friday, Iranian state media reported.

U.S. President Donald Trump urged Iran on Friday to "make a deal," warning that there will be more "death and destruction" after Israel launched deadly strikes targeting Iranian nuclear facilities.

His comments on his Truth Social platform came after Israel pounded Iran in a series of air raids on Friday, striking 100 targets.

U.S. President Donald Trump told Fox News he was aware Israel was going to conduct strikes on Iran before it happened, and stressed that Tehran "cannot have a nuclear bomb," according to the US broadcaster.

His comments to Fox came after Israel pounded Iran in a series of air raids on Friday, striking 100 targets including nuclear and military sites.

Iran's supreme leader Ayatollah Ali Khamenei swiftly appointed new Revolutionary Guards and armed forces chiefs to replace those killed in targeted Israeli strikes on Friday.

In separate decrees, Khamenei named Mohammad Pakpour to replace Hossein Salami as commander of the Islamic Revolutionary Guard Corps, and Abdolrahim Mousavi to replace Mohammad Bagheri as chief of the armed forces general staff.

The Israeli military said it hit the underground uranium enrichment centrifuges at Iran's vast Natanz facility as part of the wave of strikes it carried out on Friday.

"The underground area of the site was damaged. This area contains a multi-storey enrichment hall with centrifuges, electrical rooms and additional supporting infrastructure," the military said in a statement.

Iran sharply criticized the UN nuclear watchdog on Friday, accusing it of "silence" over Israel's strikes on its nuclear facilities and scientists.

In a statement, Iran's Atomic Energy Organization said it considers the "silence" from the International Atomic Energy Agency "as a form of cooperation with the Zionist regime," adding that the Israeli attack was a "defeat for the IAEA resulting from its unjustifiable shortcomings".

Israel attacked Iran's capital early Friday in strikes that targeted the country's nuclear program and killed at least two top military officers, raising the potential for an all-out war between the two bitter Middle East adversaries. It appeared to be the most significant attack Iran has faced since its 1980s war with Iraq.

The strikes came amid simmering tensions over Iran's rapidly advancing nuclear program and appeared certain to trigger a reprisal, with Supreme Leader Ayatollah Ali Khamenei warning that "severe punishment" would be directed at Israel. Hours later, Israel's military said it had begun intercepting Iranian drones launched in retaliation.

U.S. President Donald Trump announced late Thursday that the U.S. remains "committed to a Diplomatic Resolution to the Iran Nuclear Issue," amid soaring tensions and reports of a possible Israeli strike on Iran's nuclear facilities.

An Air India passenger plane bound for London with 244 people onboard crashed Thursday in India's northwestern city of Ahmedabad, the airline and local media reported.

Visuals on local television channels showed smoke billowing from the crash site near the airport in Ahmedabad, a city with a population of more than 5 million.

Iran and the United States will hold a sixth round of negotiations over Tehran's rapidly advancing nuclear program this Sunday in Oman, the sultanate's foreign minister said Thursday, as regional tensions have spiked in recent days.

The announcement by Oman's Foreign Minister Badr al-Busaidi comes as the U.S. is drawing down the presence of staffers who are not deemed essential to operations in the Middle East and their loved ones due to the potential for regional unrest.